Dental Problems with Buprenorphine Dissolved in The Mouth to Treat Opioid Use Disorder (OUD) and Pain

Apr 11, 2022

The U.S. Food and Drug Administration (FDA) reports that patients that use medications containing buprenorphine that are dissolved in the mouth may experience dental problems.   

Dental problems, including tooth decay, cavities, oral infections and loss of teeth, can be serious and have been reported even in patients with no history of dental issues.  

Despite these risks, buprenorphine is an important treatment option for OUD and pain, and the benefits of these medicines may outweigh the risks.  

Please see the FDA warning for more information. 

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